I am a Post-doctoral Research Associate in the institute of Biodiversity, Animal Health and Comparative Medicine at the University of Glasgow. As ecophysiologist my research interests span on integrative approaches from molecules to the whole-organism to investigate how physiological mechanisms underlie life-history trajectories in animals. Specifically, I am examining whether energy metabolism and oxidative stress are proximate causes of life history variation and underlie trade-offs. I also focus on the importance of mitochondrial plasticity in responses to environmental change. My research is pushing the boundary of ecophysiological research by combining multidisciplinary cutting-edge approaches and technological breakthroughs.
Start of an experiment to investigate the effects of dietary content in antioxidant and daily fluctuations of the thermal environment on oxidative stress in fish; with Elettra Leo, and in collaboration with Matt Slater, Alfred Wegener Institute, Germany.
Welcome Julie Nati who will determine the reaction norms of the mitochondrial oxidative capacities of minnow (Phoxinus phoxinus) in response to two co-occurring environmental stressors: elevated temperature and hypoxia; in collaboration with Tommy Norin.
It is our pleasure to invite you to attend the symposium ‘Inside the black box: the mitochondrial basis of life-history variation and animal performance’ which will be held at the Society for Integrative and Comparative Biology meeting Jan 3-7, 2018 in San Francisco, CA.
In addition to the main symposium, companion oral and poster sessions will also be held. You can opt to participate in the companion oral or poster session when submitting the abstract online. Deadline for submissions: September 6, 2017.
Great evening at the Café Scientifique for the Glasgow Science Festival. A lot of interesting discussions and a great interest for the mitochondria model (made of a potato and play doh).
Following the publication of the methodology to determine the effective P/O ratio, we now supply supplementary materials to extract and process the raw oxygen and fluorescence signals obtained from an O2k oxygraph equipped with an LED Module, with the steps required to complete the Excel template file as elaborated in Salin et al. (2016, Physio Rep).
I am officially a STEM Ambassador!
I have been awarded an Early Career Mobility Scheme from the University of Glasgow (£5k). This award allows me to visit (for 2 months) Frank Seebacher‘s lab in the University of Sydney where we will experimentally manipulate the efficiency with which the mitochondria transform energy to estimate the impact of mitochondrial efficiency on animal locomotor performance.
Oral presentation at the SICB 2017, New Orleans, LA: How Does Mitochondrial Functioning Constrain Energy Efficiency?
Acceptance of our method article on an assay that measures ROS in living animals and offers the possibility to store samples prior to analysis, so finally overcoming the main limitations of in vitro assays. We provide a detailed description of how to develop the MitoB protocol in organisms for which the method has never been applied before, with a general focus on issues that are likely to face ecologists and evolutionary biologists working on oxidative stress.
Salin, K., Auer, S. K., Villasevil, E. M., Anderson, G. J., Cairns, A. G., Mullen, W., Hartley, R. C., and Metcalfe, N. B.(2017) Using the MitoB method to assess levels of reactive oxygen species in ecological studies of oxidative stress.Scientific Reports, 7, 41228. (doi: 10.1038/srep41228) PDF
I was delighted to be part of the Women of the Future Awards in London, with so many inspirational women. I have been nominated for this UK award as one of 5 dynamic young females in the Science section.
Start of a 3-month experiment to investigate the link between mitochondrial phenotype and protein synthesis; in collaboration with Simon Lamarre, Université de Moncton, Canada.
Acceptance of our article on a new method that simultaneously quantifies both ATP production and oxygen consumption in tissue homogenates, so for the first time allowing the calculation of P/O ratios from tissue samples as small as tens of milligrams; in collaboration with Christos Chinopoulos, Semmelweis University, Hungary.
Salin, K., Villasevil, E., Auer, S., Anderson, G., Selman, C., Metcalfe, N., and Chinopoulos, C. (2016) Simultaneous measurement of mitochondrial respiration and ATP production in tissue homogenates and calculation of effective P/O ratios. Physiological Reports, 4(20), e13007. (doi:10.14814/phy2.13007) PDF